In terms of chords and melody, My Friend is significantly more complex than the typical song, having above average scores in Chord Complexity, Melodic Complexity, Chord-Melody Tension, Chord Progression Novelty and Chord-Bass Melody.
My Friend is written in the key of E Major. According to the Theorytab database, it is the 5th most popular key among Major keys and the 5th most popular among all keys. Major keys, along with minor keys, are a common choice for popular songs. The three most important chords, built off the 1st, 4th and 5th scale degrees are all major chords (E Major, A Major, and B Major). See the E Major Cheat Sheet for popular chords, chord progressions, downloadable midi files and more!